In common along with other answers to quoting the brand new variables regarding self-confident selection, i have made multiple literally unrealistic assumptions. Since BGS seemingly have apparently little affect new ? and you can p prices (Table step 1), area of the real question is the end result out of group situations on the SSW estimates. Inclusion of these issue during the suggestions for estimating selection parameters try a difficult disease. not, i observe that the latest spread to a high frequency out of a beneficial positive mutation in a people spread-over a two-dimensional ecosystem is significantly much slower than in an effective panmictic society, which suggests that there surely is a whole lot more chance for recombination so you’re able to dilute the consequences off SSWs than which have panmixia (47). This process manage therefore bring about our ? estimates to be shorter as compared to real philosophy, in addition to p rates becoming big.
Materials and techniques
Second, we have assumed “hard” sweeps, based on unique mutations, rather than “soft sweeps” based on recurrent mutations or mutations arising from standing variation (48). Lees verder