Mutations within this gene, situated on chromosome 11q22-23, try of the ovarian atrophy and amenorrhea despite normal people intimate differentiation

Xp (short-arm) genes: Deletions or disturbances from crucial areas of the new short arm off the X-chromosome (Xp11, Xp22.1-21.3) had been described in colaboration with gonadal dysgenesis and you can prienorrhea.

Zfx (X-linked zinc little finger healthy protein): Situated on Xp22.1-21.step 3, so it gene encodes an extensively shown proteins out of unfamiliar form. Zfx “knockout” mice are small, faster fertile, and now have a lower life expectancy germ cell phone number on the ovaries and you can testes.

USP9X gene (ubiquitin-certain protease nine gene): It’s found on Xp11.4, and its product is generally expressed in several tissues. Lees verder →

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